Bioavailability, Efficacy, Safety, and Regulatory Status of Creatine and Related Compounds: A Critical Review Kreider, R.B.; Jäger, R.; Purpura, M. Nutrients 2022, 14, 1035 Abstract In 2011, we published a paper providing an overview about the bioavailability, efficacy, and regulatory status of creatine monohydrate (CrM), as well as other “novel forms” of creatine that were being marketed at the time. …
Creatine Enhances Mitochondrial Function
Role of Creatine Supplementation in Conditions Involving Mitochondrial Dysfunction: A Narrative Review Marshall, R.P.; Droste, J.-N.; Giessing, J.; Kreider, R.B. Nutrients 2022, 14, 529. Abstract Creatine monohydrate (CrM) is one of the most widely used nutritional supplements among active individuals and athletes to improve high-intensity exercise performance and training adaptations. However, research suggests that CrM supplementation may also serve as a therapeutic …
Velocity-Based Training Improves Power
Velocity-Based Resistance Training on 1-RM, Jump and Sprint Performance: A Systematic Review of Clinical Trials Baena-Marín, M.; Rojas-Jaramillo, A.; González-Santamaría, J.; Rodríguez-Rosell, D.; Petro, J.L.; Kreider, R.B.; Bonilla, D.A. Sports 2022, 10, 8. Abstract Weight resistance training (RT) has been shown to positively influence physical performance. Within the last two decades, a methodology based on monitoring RT through movement velocity …
Paraxanthine Improves Cognitive Function
Dose-Response of Paraxanthine on Cognitive Function: A Double Blind, Placebo Controlled, Crossover Trial Xing, D.; Yoo, C.; Gonzalez, D.; Jenkins, V.; Nottingham, K.; Dickerson, B.; Leonard, M.; Ko, J.; Faries, M.; Kephart, W.; Purpura, M.; Jäger, R.; Wells, S.D.; Sowinski, R.; Rasmussen, C.J.; Kreider, R.B Nutrients 2021, 13, 4478. https://doi.org/10.3390/nu13124478 Abstract Paraxanthine (PXN) is a metabolite of caffeine that has recently been …
Strength Improvement Possible without Reaching Failure
Velocity-Based Resistance Training on 1-RM, Jump and Sprint Performance: A Systematic Review of Clinical Trials Baena-Marín, M.; Rojas-Jaramillo, A.; González-Santamaría, J.; Rodríguez-Rosell, D.; Petro, J.L.; Kreider, R.B.; Bonilla, D.A. Sports 2022, 10, 8. https://doi.org/10.3390/sports10010008 Abstract Weight resistance training (RT) has been shown to positively influence physical performance. Within the last two decades, a methodology based on monitoring RT through movement velocity (also …
Paraxanthine Enhances Cognitive Function
Acute Paraxanthine Ingestion Improves Cognition and Short-Term Memory and Helps Sustain Attention in a Double-Blind, Placebo-Controlled, Crossover Trial. Yoo, C.; Xing, D.; Gonzalez, D.; Jenkins, V.; Nottingham, K.; Dickerson, B.; Leonard, M.; Ko, J.; Faries, M.; Kephart, W.; Purpura, M.; Jäger, R.; Wells, S.D.; Sowinski, R.; Rasmussen, C.J.; Kreider, R.B. Nutrients 2021, 13, 3980. Abstract This study examined the effects …
Exercise and Nutritional Strategies for Weight Loss
Exercise and Nutritional Strategies to Promote Weight Loss: A Narrative Review Kreider RB. OBM Integrative and Complementary Medicine 2021;6(4):19 Abstract Obesity has historically been thought to simply be related to an imbalance between energy intake and expenditure. Weight loss recommendations have traditionally focused on reducing energy intake, maintaining either a high-carbohydrate low-fat diet or vice versa, and increasing physical activity typically …
Nutritional Strategy to Enhance Cognition in Gamers
Effects of Inositol-Enhanced Bonded Arginine Silicate Ingestion on Cognitive and Executive Function in Gamers Sowinski, R.; Gonzalez, D.; Xing, D.; Yoo, C.; Jenkins, V.; Nottingham, K.; Dickerson, B.; Humphries, M.; Leonard, M.; Ko, J.; Faries, M.; Kephart, W.; Rasmussen, C.J.; Kreider, R.B. Nutrients 2021, 13, 3758. Abstract Inositol stabilized arginine silicate (ASI) ingestion has been reported to increase nitric oxide levels while …
MCT1 rs1049434 Polymorphism in High-Intensity Endurance Performance
Putative Role of MCT1 rs1049434 Polymorphism in High-Intensity Endurance Performance: Concept and Basis to Understand Possible Individualization Stimulus Ramírez de la Piscina-Viúdez, X.; Álvarez-Herms, J.; Bonilla, D.A.; Castañeda-Babarro, A.; Larruskain, J.; Díaz-Ramírez, J.; Ahmetov, I.I.; Martínez-Ascensión, A.; Kreider, R.B.; Odriozola-Martínez, A. Sports 2021, 9, 143. Abstract Monocarboxylate transporters (MCTs) have been proposed as important mediators of the exchange between lactate …
CYP1A2 Genotype Influences Ergogenic Effects of Caffeine
CYP1A2 Genotype Polymorphism Influences the Effect of Caffeine on Anaerobic Performance in Trained Males Minaei S, Jourkesh M, Kreider RB, Forbes SC, Souza-Junior TP, McAnulty SR, Kalman D. International Journal of Sport Nutrition and Exercise Metabolism. 2021 Oct:1-6. PMID: 34611052. Abstract The purpose was to investigate the effects of CYP1A2 -163C > A polymorphism on the effects of acute caffeine …